鍏盁纾烽吀閶颁綔鐐洪嫲闆绘睜涓殑閲嶈闆昏В璩�(zh矛)锛岄毃钁楁柊鑳芥簮闋�(l菒ng)鍩熺殑蹇€熺櫦(f膩)灞曪紝鍏堕渶姹備篃鑸囨棩淇卞銆傚叾涓～閰告牴锛圫O
42-锛変綔鐐洪嫲闆绘睜闆昏В璩�(zh矛)涓殑娣诲姞鍔戯紝灏嶉浕姹犵殑灏庨浕鎬у強绌�(w臎n)瀹氭€ц捣钁楄嚦闂�(gu膩n)閲嶈鐨勪綔鐢�銆傛牴鎿�(j霉)鍖栧伐妯欐簴?HG/T 4066-2015?涓(gu墨)瀹氬惈閲�99.95%鐨勫叚姘熺７閰搁嫲涓～閰告牴鐨勯檺鍊尖墹5mg/kg銆傚洜姝�锛屽缓绔嬫簴纰恒€佺啊鍠�銆佸揩閫熷垎鏋愬井閲忕～閰告牴闆㈠瓙鐨勫惈閲忔脯瀹氭柟娉曞皪鐢熺敘(ch菐n)鍑烘€ц兘鏇村劒(y艒u)璩�(zh矛)鐨勯嫲闆绘睜鎰忕京閲嶅ぇ銆�
鐩墠纭吀鏍癸紙SO
42-锛夊惈閲忕殑妾㈡脯鏂规硶涓昏鏈夋瘮婵佹硶鍜岄洟瀛愯壊璀滄硶锛岀敱浜庣～閰搁媷姣旀縼娉曞彈妯ｅ搧鍩洪珨骞叉摼杓冨ぇ锛屽洜姝ゅ緢闆ｆ簴纰哄垎鏋愭ǎ鍝佺殑寰噺纭吀鏍瑰惈閲�锛屼笖閲嶅京鎬ц純宸�锛涙湰鏂规硶閲囩敤澶╃憺鍎€鍣ㄦ柊涓€浠ｉ洟瀛愯壊璀滃剙TIC-660娓畾鍏盁纾烽吀閶版ǎ鍝佷腑鐨勭～閰告牴锛圫O4
2-锛夊惈閲忥紝瑭叉柟娉曟鍑洪檺鈮�0.18渭g/mL锛屼繚鐣欐檪闁揜t瀹氭€ч噸寰╂€SD鐐�0.15%锛孲O
42-宄伴潰绌嶅畾閲忛噸寰╂€SD鐐�3.45锛�,妯ｅ搧鍔犳鍥炴敹鐜囩偤109.5%锛岀窔鎬х浉闂�(gu膩n)绯绘暩(sh霉)r鐐�0.99996銆�
瀵﹂绲�(ji茅)鏋滆〃鏄�锛岃┎鏂规硶绨″柈婧栫⒑銆佸揩閫熼珮鏁�锛屽彲鏈夋晥鎳夌敤浜庢柊鑳芥簮浼佹キ(y猫)涓棞(gu膩n)浜庡叚姘熺７閰搁嫲涓～閰告牴闆㈠瓙鐨勭鎺х洠(ji膩n)娓€�
1.鍎€鍣ㄧ啊浠�
TIC-660闆㈠瓙鑹茶瓬鍎€鏄ぉ鐟炲剙鍣ㄥ湪TIC-600鐨勫熀绀�(ch菙)涓�锛屾帹鍑虹殑鍏ㄦ柊涓€娆炬€ц兘鏇翠匠鐨勯洟瀛愯壊璀滃剙锛涘畠鍏锋湁闆欐サ闆昏矾銆侀浕纾侀枼閫叉ǎ銆佸彲鎼級鑷嫊娣嬫礂娑茬櫦(f膩)鐢熷櫒銆佸悓鏅傚彲鍏煎瀹夊煿妾㈡脯鍣�銆佺传澶栨娓櫒绛夊绋娓櫒锛屾豢瓒充笉鍚岀殑妯ｅ搧娓│闇€姹�銆�
TIC-660鏂板瀷闆㈠瓙鑹茶瓬鍎€
2.娓│鍘熺悊
灏囪檿鐞嗗ソ鐨勬ǎ鍝佹憾娑叉敞鍏ュ埌瀹氶噺鐠�(hu谩n)鍚庯紝鍦ㄦ祦鍕曠浉鐨勪綔鐢ㄤ笅娴佺稉(j墨ng)鑹茶瓬鏌�锛岄€氶亷闆㈠瓙浜ゆ彌灞ゆ瀽鏌辩殑闆㈠瓙浜ゆ彌鍔熻兘锛屽皣妯ｅ搧涓殑闆㈠瓙鏍规摎(j霉)澶у皬銆侀浕鑽�銆佽Κ鍜屾€х瓑鐗规€ц渚濇鍒嗛洟鍑轰締锛岀稉(j墨ng)闆诲皫妾㈡脯鍣ㄦ娓悗锛屼互淇濈暀鏅傞枔瀹氭€�锛屽緱鍒版績搴﹀拰宄伴潰绌嶄箣闁撶殑姝ｆ瘮渚嬮棞(gu膩n)绯汇€�
3.瀵﹂閮ㄥ垎
3.1涓昏鍎€鍣ㄥ強瑭﹀姂
TIC-660鍨嬮洟瀛愯壊璀滃剙锛氭睙铇囧ぉ鐟炲剙鍣ㄨ偂浠芥湁闄愬叕鍙�銆�
妯欐簴婧舵恫锛�1000mg/L纭吀鏍规婧栨憾娑层€�
闄伴洟瀛愯壊璀滄煴锛�4mm*250mm锛�5渭m锛�锛�
娣嬫礂娑查噰鐢ㄧ⒊閰搁垑鍜岀⒊閰告矮閳夋贩鍚堟憾娑查厤鍒躲€�
3.2妯ｅ搧鍓嶈檿鐞�
鍦ㄥ共鍑堢殑PP鐡朵腑婧栫⒑绋卞彇1g锛堢簿搴�0.1mg锛夊叚姘熺７閰搁嫲妯ｅ搧锛屽姞瓒呯磾姘村埌绱�20g绋遍噸锛堢█閲嬬磩20鍊嶏級锛屾尟钑╂悥鍕�锛岀洿鑷虫ǎ鍝佸畬鍏ㄦ憾瑙�銆傛憾娑查亷0.22渭m姘寸郴閲濆紡閬庢烤鍣�锛岄€叉ǎ鍗冲彲銆�
3.3纭吀鏍归洟瀛愭婧栨憾娑查厤鍒讹細
纭吀鏍归洟瀛愭婧栨憾娑查噰鐢ㄦ搴︽績搴︾殑鏂瑰紡閫愮礆绋€閲嬬偤0.5渭g/mL銆�1.0渭g/mL銆�5.0渭g/mL銆�10.0渭g/mL銆�20.0渭g/mL鐨勬婧栨憾娑诧紱瑭宠琛�1銆�
琛�1. 纭吀鏍规婧栨洸绶氭績搴︼紙渭g/mL锛�
3.5瀵﹂绲�(ji茅)鏋�
3.5.1妯欐簴鏇茬窔
鎸夌収纭吀鏍瑰悇婵冨害榛炰緷娆￠€叉ǎ锛岃▓绠楀叾宄伴潰绌�锛屼互婵冨害鍜屽嘲闈㈢⿳绻埗妯欐簴鏇茬窔锛岀窔鎬х浉闂�(gu膩n)绯绘暩(sh霉)鐐�0.99996锛岀祼(ji茅)鏋滆┏瑕嬪湒1銆�
鍦�1.SO42-妯欐簴鏇茬窔
3.5.2妾㈠嚭闄愯垏瀹氶噺闄�
鐢�0.5渭g/L纭吀鏍规婧栨憾娑茶壊璀滃湒濡傚湒2鎵€绀�锛岀敱鑹茶瓬宄伴珮鍜屽熀绶氬櫔鑱�锛屾寜鍏跺叕寮廋min=2H
N脳CV/25H瑷堢畻鍏舵渶浣庢鍑洪檺鐐�0.009渭g/mL锛屽畾閲忛檺鐐�0.036渭g/mL銆�
鍦�2 0.5渭g/mL纭吀鏍规婧栨憾娑茶壊璀滃湒
3.5.3閲嶅京鎬ц€冨療
鍙�0.5渭g/L纭吀鏍规婧栨憾娑查噸寰╅€叉ǎ6娆�锛岃€冨療淇濈暀鏅傞枔鍜屽嘲闈㈢⿳鐨勯噸寰╂€�锛孯SD绲�(ji茅)鏋滆┏瑕嬭〃3銆�
琛�3 淇濈暀鏅傞枔鍜屽嘲闈㈢⿳閲嶅京鎬э紙n=6锛�
3.5.4妯ｅ搧娓│鍙婃ǎ鍝佸姞妯欐脯瑭�锛屽叾娓│璀滃湒濡傚湒3-1銆�3-2锛屾脯瑭︾祼(ji茅)鏋滆琛�4銆�
鍦�3-1 鍏盁纾烽吀閶版ǎ鍝佷腑纭吀鏍圭殑瀵︽脯璀滃湒
鍦�3-2鍏盁纾烽吀閶版ǎ鍝佷腑鐨勭～閰告牴鍔犳1渭g/mL璀滃湒
琛�4 瀵︽脯鍏盁纾烽吀閶版ǎ鍝佷腑纭吀鏍圭殑鍚噺鍙婂姞妯�1渭g/mL鐨勬脯瀹氬€煎強鍥炴敹鐜�
4.绲�(ji茅)璜�
鏈枃閫氶亷TIC-660闆㈠瓙鑹茶瓬鍎€蹇€熸簴纰虹殑鍒嗘瀽浜嗛嫲闆绘睜鍏盁纾烽吀閶颁腑鐨勭～閰告牴闆㈠瓙鐨勫惈閲�锛岀祼(ji茅)鏋滆〃鏄�锛岃┎鏂规硶妾㈠嚭闄愪綆锛岄噸寰╂€уソ锛屼笖鍓嶈檿鐞嗘柟娉曟搷浣滅啊鍠�锛屽彲鐢ㄤ簬閶伴浕姹犱腑寰噺纭吀鏍癸紙SO
42-锛夌殑鏈夋晥鐩�(ji膩n)娓€�
5.鍙冭€冩枃鐛�
銆�1銆慓B/T 19282-2014 鍏盁纾烽吀閶扮敘(ch菐n)鍝佸垎鏋愭柟娉�锛屼腑鍦嬪湅瀹舵婧栧寲绠＄悊濮斿摗鏈冪櫦(f膩)甯冿紝2015銆�
